Solubilization and renaturation of biologically active human bone morphogenetic protein-4 from inclusion bodies
نویسندگان
چکیده
منابع مشابه
MB109 as bioactive human bone morphogenetic protein-9 refolded and purified from E. coli inclusion bodies
BACKGROUND The development of chemical refolding of transforming growth factor-beta (TGF-β) superfamily ligands has been instrumental to produce the recombinant proteins for biochemical studies and exploring the potential of protein therapeutics. The osteogenic human bone morphogenetic protein-2 (hBMP-2) and its Drosophila DPP homolog were the early successful cases of refolding into functional...
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ژورنال
عنوان ژورنال: Biotechnology Reports
سال: 2018
ISSN: 2215-017X
DOI: 10.1016/j.btre.2018.e00249